Acetaminophen, aspirin, and ibuprofen are three common pain relievers available over-the-counter. Aspirin is the oldest, used for practically every ache and pain until the availability of two alternatives, nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen and naproxen) and acetaminophen, which cause less stomach irritation. All three have benefits and uses that make them unique, but the problems with their use are just as diverse. In this section, learn about acetaminophen safety with children, which includes fast facts about the medicine. You will also find information on a national Know Your Dose campaign that stresses the importance of recognizing acetaminophen as an ingredient in more than 600 different prescription and OTC medicines. Another section discusses aspirin and aspirin containing products, which includes a list of safety tips to follow. Also learn more about the heart risks associated with nonsteroidal anti-inflammatory medicines.